Atherosclerosis:
Risk Factors, Diagnosis, and Treatment
Salzburg, Austria, July 7-10, 2002 |
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FOREWORD
On behalf of the European Atherosclerosis Society we
were fortunate to organize the 73rd Annual Congress
in Salzburg. This beautiful city, which is located in the heart of Europe
has a long lasting tradition in bringing together artists, musicians and
scientists from different countries. Mozart was born in Salzburg, and
Paracelsus, the famous physician of the Middle Ages is said to have spent
the final years of his life here. Year after year, this marvellous city is
among the top destinations of international tourism. We are convinced it
is just the right place for bringing the leading experts in
atherosclerosis research together. Although scientists are often believed
to have no interest in art and music, we know this isn’t true. And it is
the arts and the music that Austrians have been cultivating and they enjoy
to share their traditions with others.
What do atherosclerosis and researchers searching for a
cure for this disease have in common? The former is multifactorial, the
latter is coming from a multitude of disciplines and works in an ever
increasing number of speciality fields. This is reflected by the wide
variety of topics discussed at the 73rd EAS Congress. Although lipid
lowering therapy, especially statins have shown tremendous benefit in
reducing mortality and cardiovascular morbidity, coronary artery disease
remains the biggest killer in industrialized nations. Therapy for CAD
ranges from simple diet to highly specialized treatments like
extracorporeal plasma delipidation. Basic research and resulting clinical
trials have tought us so much about atherosclerosis but now we are facing
new challenges: Targets, pleiotropic effects, interactions of substances,
too many novel markers for atherosclerosis and gene therapy to name just a
few. Statins in fact were the focus of several workshops and educational
symposia. This 73rd EAS congress brought together
the leading experts in the field of atherosclerosis research and
cardiology presenting brand new data of their most recent investigations.
Scientists and physicians from many different parts of the world were
congregating and sharing their different views and opinions on this
challenging subject. For the first time, representatives of Ethnomedicine
and Medical Anthropology were invited and have given new insights from a
different perspective in a special workshop on Ethnomedicine and obesity.
Amongst many others, genetic factors of atherosclerosis,
the homeostasis of cell cholesterol, immunological aspects of
atherosclerosis, hemostatic factors, lipid oxidation and risk factors of
diabetes mellitus were only some of the topics for workshops, plenary
lectures and poster presentations.
This book is a document of science presented at the 73rd
EAS Congress and is a selection of invited lectures and free
communications presented in Salzburg.
Editors in Chief:
Prof. Dr. Gert M. Kostner, University of Graz and Prof. Dr. Karam M.
Kostner, University Hospital of Vienna
INDEX
Atherosclerosis and
Cardiovascular Risk Factor
Role of Acyl-coenzyme A: Cholesterol
Acyltransferase (ACAT) in Cholesterol Gallstone Pathogenesis
J.L. Smith, K. Rangaraj, S.P. Scott, D.J.
Maclean and J. de Jersey
Ruptured Plaques, Ulcers and Thickened Intima: That‘s how Man look
Inside
I. Asmussen
Classical Risk Factors for Ischemic Heart Disease and C-Reactive
Protein in Acute Coronary Syndromes
L. Bronze, J. Monge, A. Anăo, J. Galvăo, C.
Ferreira, J. Azevedo and A. Aleixo
The Distributions of Blood Lipids, Apolipoproteins A-I and B,
Homocysteine and Fibrinogen By Gender: The "ATTICA" Study
C. Pitsavos, T. Sergentanis, D.B.
Panagiotakos, C. Chrysohoou, A. Zeimbekis, I. Papaioannou, S. Vellias, M.
Toutouza, C.I. Stefanadis and P.K. Toutouzas
Analysis and Study of Sudden Cardiac Deaths Due to Atherosclerosis, in
the County of Trikala, Greece
Th. Galeas, I. Hatzizisis, Hr. Zisis, S.
Mylonas and A. Papadopoulos
Physical Activity Modulates the Effect of Apoe Genotype on HDL-C
Concentrations in a Spanish Population
D. Corella, M. Guillén, A. Godoy, J.V. Sorlíl,
O. Portolés, C. Sáiz, O. Coltell and J.M. Ordovás
Fatty Acid-induced Endothelial Cell Activation
B. Hennig, V. Saraswathi, A. Daugherty and M.
Toborek
Effectiveness of Action on Prevention in the Southern Poland
Epidemiological Survey. Distribution of Blood Pressure in Relation to Age
and Gender
K. Kozakiewicz, M. Sosnowski, T. Pawlowski,
K. Zaorski, P. Garbocz and M. Tendera
Patient Models of Coronary Heart Disease
G. Krstacic, A. Krstacic and M.
Jembrek-Gostovic
Local Cerebral Blood Flow in Patients with Hyperlipidemia and
Cerebrovascular Disease Prior To and After Simvastatin Treatment
B. Lipovetsky, G. Kataeva and A. Korotkov
Predictors for Cardiovascular Events, in Subjects with Familial
Hypercholesterolemia: 15-Year Follow-up (1987-2002)
C. Pitsavos, J. Skoumas, C. Chrysohoou, D.B.
Panagiotakos, I. Papaioannou, M. Toutouza, C.I. Stefanadis and P.K.
Toutouzas
Psychosocial Factors and Acute Coronary Syndromes: Their Importance By
Gender. The Cardio2000 Study
D.B. Panagiotakos, C. Pitsavos, C. Chrysohoou,
T. Kyratzoglou, N. Marinakis, S. Vellias, K. Tzioumis, A. Moraiti, C.I.
Stefanadis and P.K. Toutouzas
The Inverse Association Between Educational Status and Several
Established and Emerging Cardiovascular Risk Factors, at Population Level:
The "Attica" Study
D.B. Panagiotakos, C. Pitsavos, C. Chrysohoou,
J. Skoumas, M. Toutouza, A. Zeimbekis, N. Papaioannou, C.I. Stefanadis and
P.K. Toutouzas
The Impact of Aquatic Exercise on Cardio-respiratory, Renal and Lipid
Parameters in Chronic Renal Failure Patients
Y. Pechter, J. Maaroos, M. Zilmer, K. Zilmer,
S. Mesikepp, A. Veraksits and M. Ots
PPAR Gamma, Leptin And Endothelial Cell - Mediated Angiogenesis
A. Polus, E. Piątkowska,
J. Grzybowska and A. Dembińska-Kieć
Endothelial Dysfunction in Workers Exposed to Lead
A. Skoczyńska,
R. Poręba
and A. Derkacz
The Serum Transforming Growth Factor-beta (TGF-beta) Level in Coronary
Heart Disease Patients
E. Romuk, B. Skrzep-Poloczek, C.
Wojciechowska, A. Tomasik, J. Szygula, E. Birkner and J. Wodniecki
Angioscopic Observation of the Atherosclerosis of Cholesterol-Fed
Ovariectomised Japanese Monkeys
R. Torii, N. Ikeda, T. Ito, S.Y. Eguchi,
Yamada and M. Shiomi
Functional and Biochemical Correlation Between Endothelial Dysfunction
and Intima-Media Thickness (IMT).
E. Bernal, A. Bajo-Martínez, A.
Ugalde-Canitrot, M. Calbacho, I. Marín, J. Haurie, C. Mendieta and J.
Sabán-Ruiz
Trend risk factors of Coronary Prevention Study in Republika Srpska -
Bosnia and Herzegovina (ROSCOPS)
D. Vulic, Lj. Keric, B. Vulic, M. Krneta and
Z. Pavic
Sex-related Differences in Cardiovascular Risk Factors Among Serious
Depressive Patients
A.F.G. Cicero, M. Forghieri, G. Savino, F.
Cipressi and R. Arletti
Free Radicals, Oxidation and
Antioxidants
Endothelium and Oxidised Lipoproteins
A.L. Catapano, A. Pirillo, F. Pellegatta and
G.D. Norata
Pathophysiological Role of Lipid Peroxidation in Patients with Acute
and Chronic Coronary Syndromes
E. De Fanti, M. Rugolotto, M. Barbiero, G.
Rigatelli and R. Schiavon
HDL and Oxidized Lipids as the Modulators of Platelet Receptor Activity
J. Hartwich, M. Motyka, A. Gruca, M. Bzowska,
J. Skrzeczyńska,
J. Pryjma, G. Schmitz, N. Leitinger,
Ł.
Partyka and A. Dembinska-Kiec
Antioxidant Protection in Diabetic Retinopathy
T.M. Francuz, A. Telega, A. Wójcik, B. Posielężna,
R. Grabowska-Bochenek, J. G. Gmiński,
K. Siemianowicz and M. Machalski
How a Receptor for Oxidized Low Density Lipoproteins Works in Human. –
Insights from Human Genetic CD36 Deficiency –
K. Hirano, T. Kuwasako, Y. Nakagawa-Toyama,
T. Sugimoto, M. Ishigami, N. Sakai, H. Hiraoka, S. Yamashita, and Y.
Matsuzawa
Antioxidant Enzymes Activities in Patients with Familial Lecithin:
Cholesterol Acyltransferase (LCAT) Deficiency (FLD)
B. Idzior Waluś,
T. Wesołowska,
M. Waluś,
W. Rostworowski and J. Sieradzki
Oxidative Modification of LDL and HDL Lipoproteins in Patients with
Familial Lecithin: Cholesterol Acyltransferase (LCAT) Deficiency
B. Idzior-Waluś,
J. Hartwich, W. Rostworowski, T. Wesołowska,
A. Dembińska-Kieć
and J. Sieradzki
Peroxynitrite and Myocardial Adenosine Production-Protective Effect of
Melatonin
G. Kocic, R. Kocic, G. Bjelakovic, T.
Jevtovic, R. Pavlovic, D. Pavlovic, D. Sokolovic, T. Cvetkovic, I.
Stojanovic and V. Djordjevic
Free Radical-Induced Modification of Human Fibrinogen: Implications for
Atherosclerosis
B. Lipinski and I. Lipinska
Effects of Oxidised LDL on Murine Preadipocyte 3T3.L1 Differentiation
R. Varě, R. Masella, M. D’Archivio, B.
Scazzocchio, F. Maialetti, G. Leto and C. Giovannini
The Susceptibility of LDL to Oxidation by Myeloperoxidase is Related to
the Differential Count of Monocytes
N. Moguilevsky, K. Zouaoui Boudjeltia, Y.
Carpentier, A. Bollen, D. Brohee, M. Vanhaeverbeek and J. Ducobu
Correlation Between Serum Levels of Ferritin and Alpha-Tocopherol with
the Degree of Oxidant Stress in a Population with Elevated Cardiovascular
Risk
M. Calbacho, A. Ugalde-Canitrot, A.
Bajo-Martínez, E. Bernal, B. González, M. Díaz, L. González, R. Fabregate
and J. Sabán-Ruiz
Differential Impact of Non-Oxidative and Oxidative Lipid Metabolism on
Endothelin and PAI-1 Plasma Levels in a Population with Elevated
Cardiovascular Risk
A. Ugalde-Canitrot, M. Calbacho, E. Bernal,
A. Bajo-Martínez, L. González, R. Fabregate Nurse and J. Sabán-Ruiz
Myeloperoxidase Oxidised-LDL Delay Fibrin Clot Lysis on the Surface of
Endothelial Cells
K. Zouaoui Boudjeltia, N. Moguilevsky, P.
Delree, M. Alvarez, J. Ducobu, P. Cauchie, M. Guillaume, M. Vanhaeverbeek,
D. Brohee and C. Remacle
Homocisteine
Principles of Homocysteine Metabolism in Health and Disease
W. Herrmann
Homocysteine As a Risk Factor of Atherosclerotic Lesion
R. Santos, J. Freitas, M. Macedo, A. Monteiro,
L. Belo, I. Rebelo, E. Castro and A. Feitas
Homocysteine As Predictor of Clinical Events in Patients with Previous
Myocardial Infarction
I. Seljeflot, M. Hurlen, B. Christensen, M.
Fjeldly, L.G. Klćboe and H. Arnesen
Paradoxical Antioxidant Effect of Homocysteine in Patients with Classic
Cardiovascular Risk Factors
A. Bajo-Martínez, E. Bernal, M. Calbacho, A.
Ugalde-Canitrot, J.F. Martín-Lázaro, O. Sanchez, C. Santiuste, R.
Fabregate and J. Sabán-Ruiz
Blood Homocysteine and Kidney Involvement in Type 1 and Type 2 Diabetes
Mellitus
O. Giampietro, D. Calvi, G. Forotti, E.
Boldrini, F. Marchini, L. Moretti and E. Matteucci
Gene and Genetics
Screening Asp9-Asn Polymorphism in Exon 2 of Lipoproteinlipase Gene in
Familial Combined Hyperlipidemia
A. Hernández-Mijares, M. Casado, M.L.
Martínez-Triguero, A. López-Ruiz, E. Solá, S. Garzón, A. López-Gutierrez
and C. Morillas
Mapping of Quantitative Trait Loci Involved in Atherosclerosis in the
Mouse
R. Korstanje and B.J. Paigen
Isolation and Characterization of Non-Uniform Shear Stress- Responsive
Genes, RECS
H. Nojima, H. Yoshisue, H. Zhao, T. Ohya, S.
Kimura, S. Yamashita and Y. Matsuzawa
Lipoprotein(a)
Has Lp(a) Any Physiological Function?
G.M. Kostner
Lipoprotein a as an Independent Risk Factor for Coronary Artery Disease
in Patients with Angina
E. Hatzinikolaou, I. Kaprinis, A. Hotidis, D.
Tziakas, I. Apostolou, I. Papadopoulos, G. Katsaris and D. Hatseras
The Change of Composition As Well As the Concentration of Serum Lp(a)
Can Be a Sign for End-stage Renal Failure
K. Miho and A. Masato
Lipid-Apheresis in Two Patients with Elevated Lp(a) and Progressive CHD
A. Vogt, U. Kassner, H.-P. Thomas, C.
Schliesser and E. Steinhagen-Thiessen
Treatment of Atherosclerosis
and Hyperlipoproteinemia
A Novel Extracorporeal Plasma Delipidation Procedure for the Treatment
of Atherosclerosis
K.M. Kostner, J.L. Smith and B.E. Cham
Short Term Effects of Atorvastatin on Coagulation and Inflammation
W.F. Riesen, W. Korte, H. Engler and G.
Noseda
Undertreatment of Dyslipoproteinemia in Cardiovascular Diseases
P. Schwandt and G-M. Haas
The Impact of Aggressive Lipid Lowering Therapy Upon Cholesterol
Biosynthesis and Absorption
V. Bláha, R. Hyšpler, M. Bláha, D. Solichová,
P. Žďánský,
E. Havel, P. Vyroubal, Z. Zadák and J. Malý
Effects of Simvastatin 40 mg on Blood Pressure in Hypercholesterolemic
Patients
A. Branchi, A.M. Fiorenza, A. Torri, C. Berra,
E. Colombo, A. Rovellini and D. Sommariva
Simvastatin Prevents AT1 Receptor Gene Overexpression in Human Vascular
Smooth Muscle Cells and Endothelial Cells Stimulated with k-Elastin
T.M. Francuz, E. Kotrys-Puchalska, T. Jurczak,
T. Gawlik, J.G. Gminski and M. Machalski
Effectivity of Simvastatin on Lipid Changes and their Mutual
Correlation
A. Kalvelis and G. Bahs
The Improvement of Endothelial Function After Quinapril and L-Arginine
Therapy
M. Malczewska-Malec, M. Rajzer, A. Zdzienicka,
K. Kawecka-Jaszcz and A. Dembińska-Kieć
Effects of Simvastatin on Moieties of Extrinsic Coagulation Pathway in
CAPD Patients
J. Malyszko, J.S. Malyszko, T. Hryszko and M.
Mysliwiec
A Study to Demonstrate the Utility of HELP LDL Apheresis Treatment for
Patients with Non-ST Elevation Acute Coronary Syndrome
P. Moriarty, C. Gibson, K. Flechsenhar, M.
Mayo, J. Vacek, P. Tadros, S.Owens and P. Delafontaine
Atorvastatin and Pravastatin in Non ST Elevation Acute Coronary
Syndrome. Effect on Platelet Aggregation and Markers of Inflammation
E. Pokrovskaya, N. Vaulin, N. Gratsiansky, O.
Averkov and A. Deev
New Insight Into Non-Statin Prevention and Treatment of Atherosclerosis
I.A. Sobenin, I.V. Suprun and A.N. Orekhov
Long-term Combined Statin-fibrate Treatment of Mixed Hyperlipidaemia:
Safety and Efficacy
M. Zeman, A.
Žák, S.
Romaniv, E. Tvrzická, M. Vecka, T. Vařeka,
and K. Hrubant
A Comparative Study of the Efficacy and Safety of Atorvastatin,
Pravastatin, Lovastatin and Gemfibrozil in the Treatment of Hyperlipidemic
Patients
A.I. Hatzitolios, Ch.F. Delivoria, M.E.
Archaniotaki, Ch.G. Savopoulos, A.D. Kounanis, Th.G. Kallinikidis,
A.G.Ziakas and A.D. Benis
Long-term (14-years) Continuous Application of Statins by the Patients
with Hypercholesterolaemia
G.A. Konovalov and S.N. Pokrovsky
Beneficial Effect of Atorvastatin Therapy in Diabetics
R. Kocic, D. Pavlovic, G. Kocic and N.M.
Lalic
The Influence of Sodium Monoketocholate on Hypolipidemic Effects of
Lovastatin in Healthy and Diabetic Rats
S. Kojic-Damjanov, M. Djeric and M. Mikov
A Combined Treatment of Statins and H.E.L.P. apheresis for Treatment of
Cardiac Allograft Vasculopathy
B.R. Jaeger, P. Braun, D. Nagel, J.W. Park,
D.B. Gysan, M. Oberhoffer, K.P. Mellwig, G. Bahlmann, F. Heigl, R.
Heinzler, H. Militzer, P. Moriarty, S. Schütterle, H. Tachezy, E. Kreuzer,
M.C. Deng, B. Reichart and D. Seidel
Lipid and Lipoprotein
Metabolism
Molecular Mechanism of Cholesterol Efflux – Involvement of a Member of
the Rho GTPase Family, Cdc42 –
S. Yamashita, K-I. Hirano, K. Tsukamoto, A.
Matsuyama, F. Matsuura, M. Ishigami, N. Sakai and Y. Matsuzawa
High Density Lipoproteins Cholesteryl Esters Turnover in Dogs Using
Stable Isotopes with an Improved Lipoproteins Isolation Method
E. Bailhache, K. Ouguerram, P. Maugere, M.
Krempf, P. Nguyen and T. Magot
Atherogenicity of Lipoprotein Lipase in Transgenic Rabbits
J. Fan, T. Ichikawa, H. Unoki, J. Liang, T.
Koike, X. Wang and T. Watanabe
A Flow Cytometric Procedure to Measure Functional LDL Receptors for
Diagnosis of Familial Hypecholesterolemia
H. Hattori, M. Nagano, K. Kawamura, J. Ishii,
M. Tsuji, F. Iwata, T. Yamamura, Y. Miyake, T. Egashira, T. Okada, J.A.
Cooper, N.E. Miller, M. Emi and A. Yamamoto
Moesin-like HDL/Apo A-I-Binding Protein on Macrophages
A. Matsuyama, N. Sakai, H. Hiraoka, S.
Yamashita and Y. Matsuzawa
Activation of Lecithin Cholesterol Acyl Transferase (LCAT) by
Apolipoproteins
S. Roosbeek, F. Peelman and M. Rosseneu
Inflammation and Immunological
Aspects of Atherosclerosis
Inflammatory Activation of Vascular Cells: Cellular and Molecular
Mechanisms
B.R. Binder
Phospholipase A 2 Enzymes in Atherosclerosis
E. Hurt-Camejo, B. Rosengren, H. Peilot, C.
Hallberg and G. Camejo
Infection and Atherosclerosis – The Possible Role of Antibiotics in
Coronary Heart Disease Treatment
Ž.
Reiner, E. Tedeschi-Reiner and T. Anić-Milić
Augmented Monocytic Proinflammatory Cytokines in Acute Coronary
Syndromes: Relation with Plaque Inflammation and Rupture and with
Neointimal Thickening after Stenting
J.M. Bosmans, A.J. Schuerwegh, K.M. Cromheeke,
L.S. De Clerck, F.L. Wuyts, C.H. Bridts, V. Conraads, M.M. Kockx, W.J.
Stevens and C.J. Vrints
Chlamydia pneumoniae and Inflammation
V. Hoymans, J. Bosmans, D. Ursi, M. Altwegg,
W. Martinet, L. De Clerck, W. Stevens, E. Van Marck, M. Ieven and C.
Vrints
Does Inflammation Play Important Role in Pathogenesis of
Atherosclerosis and Its Clinical Outcome?
I. Burazor and M. Burazor
Long-term Endothelial Impact of Chlamydia pneumoniae Infection
D. Coca-Robinot, E. Sánchez-Largo, J.
Gónzalez, A. Ugalde-Canitrot, M. Calbacho, E. Bernal and J. Sabán-Ruiz
Suppression of Inflammation Markers in Obese (ob/ob) Mice
Z. Berke, M. Kjerrulf and E. Hurt-Camejo
Serum TNF a
and Its Soluble Receptors I and II in the Postmenopausal Women (PMW) with
a Known Risk of Atheromatosis
R. Dybkowski, J. Krzysiek, T. Milewicz, A.
Janczak-Saif, G. Krzysiek, K. Sztefko, M. Radecka and M. Kacprzak
The Benefits From Physical Activity on Anthropogenic and Inflammatory
Markers: The "Attica" Study
C. Chrysohoou, C. Pitsavos, D.B. Panagiotakos,
J. Skoumas, M. Toutouza, S. Vellias, C.I. Stefanadis and P.K. Toutouzas
C-Reactive Protein Concentrations Are Decreased By Weight and Visceral
Fat Reduction
R. Poledne, A. Dvořáková,
P. Suchánek, P. Stávek and J. Tintěra
Tumor Necrosis Factor- Alpha – The Missing Link Between Obesity and
Insulin Resistance?
D. Pupek-Musialik, P. Bogdański,
M. Łuczak,
W. Bryl and M. Cymerys
Association of the Anti Inflammatory Action of Interleukin 10 with
Metalloproteinases and Other Inflammatory Markers in Acute Coronary
Syndromes
D.N. Tziakas, G.K. Chalikias, E.I.
Hatzinikolaou, E.D. Papadopoulos, G.A. Tripsiannis, E.D. Papadopoulou,
I.K. Tentes, E.I. Bakalopoulou – Kontoleon and D.I. Hatseras
Lipids and Carotid Atherosclerosis in Systemic Lupus Erythematosus (SLE):
A Case-Control Study
P. Valdivielso, M. Macias, M. Haro, A.
Fernández-Nebro, J.J. Gómez-Doblas and P. González-Santos
Dietary Copper Deficiency Decreases Monocyte Expression of CD11b
(MAC-1) in Normocholesterolaemic Rabbits
D. Lamb and G. Ferns
Immunisation with Bacillus Calmette-Guerin Enhances Aortic
Atherosclerosis in Chronic Low Level Hypercholesterolaemic Rabbits
D. Lamb, M. Tickner, W. El-Sankary, S.
Hourani, L.-J. Reynolds and G. Ferns
The Immunology of Atherosclerosis
G. Wick, C. Mayrl, G. Pfister and M. Knoflach
Thrombotic and Hemostatic
Factors in Atherosclerosis
Body Cholesterol Homeostasis and Pools. Their Clinical Significance
C. Moutafis
MTHFR Polymorphism in Patients with Cerebrovascular Insult and Deep
Venous Thrombosis
E. Topic, M. Turek-Cubrilo, A. Begonja, A.-M.
Simundic, V. Demarin, V. Stančić
and I. Zuntar
The Influence of Tissue Plasminogen Activator on the Levels of Matrix
Metalloproteinases and Their Inhibitor. Association Between Proteolytic
and Fibrinolytic Mechanism During a Myocardial Infarction
D.N. Tziakas, G.K. Chalikias, E.I.
Hatzinikolaou, E.D. Papadopoulos, G.A. Tripsiannis, E.D. Papadopoulou,
I.K. Tentes, E.I. Bakalopoulou – Kontoleon and D.I. Hatseras
Diabetes Mellitus and
Atherosclerosis
Optimal Treatment of Dyslipidemia in Patients with Type 2 Diabetes
M.-R. Taskinen
Insulin and Other Atherosclerotic Risk Factors in a Portuguese
Population at Cardiovascular Risk
L.L. Faleiro, M.C. Martins, M.O. Rodrigues,
M.T. Seixas and A.E. Fonseca
Endothelium Dysfunction Markers in Patients with Diabetic Retinopathy
T.M. Francuz, A. Telega, M. Syzdół,
K. Siemianowicz, J.G. Gmiński
and M. Machalski
Impaired Fasting Glucose and Myocardial Infarction
Z. Rasic-Milutinovic, B. Pencic, Z. Gluvic
and N. Milic
Hypertension
Restoring the Balance Between the Endothelin System and the NO System
in Coronary Artery Disease
T. Neunteufl
The Assessment of Endothelin-1 Plasma Activity in Young, Hypertensive
Patients after Angiotensin Converting Enzyme Inhibitor Treatment
W. Bryl, A. Miczke, P. Bogdański,
M. Łuczak,
M. Cymerys and D. Pupek-Musialik
b 2 or b3
Receptor Gene Polymorphisms and Cardiovascular Risk
L. Forga, M.S. Corbalán, M. Palacios, A.
Rivero, A. Marti, M.A. Martinez-Gonzalez and J.A. Martínez
Hypertension, Postprandial Lipemia and Gene Polymorphism in Obese
Families
M. Malczewska-Malec, M. Kwaśniak,
I. Leszczyńska-Gołąbek,
B. Kieć-Wilk,
Ł.
Partyka and A. Dembińska-Kieć
Obesity and Nutrition
Obesity and Fatness among the Azande
A. Prinz
Large Body Size – A Polynesian Perspective
N.J. Pollock
The Treatment of Obesity with Traditional Chinese Medicine
B. Kostner
The Effect of Mediterranean Diet on Clinical, Biochemical Markers
Related to Cardiovascular Risk: The "ATTICA" Study
C. Chrysohoou, C. Pitsavos, D.B. Panagiotakos,
J. Skoumas, M. Toutouza, A. Zeimbekis, C.I. Stefanadis and P.K. Toutouzas
6-Months Follow-up of 105 Women Treated with Soy Isoflavones Because of
a Climacteric Syndrome
O. Iommelli, G. Tomasillo and A.F.G. Cicero
Palatability and Acceptability of a Low Dose Soy Protein/ b-Sitosterol
Association As Cholesterol Lowering Agent
A.F.G. Cicero, M.P. Panourgia, A. Fiorito, S.
Linarello, S. D’Addato and A. Gaddi
Efficacy and Metabolic Effects of Two Diets For Treating Obesity
F. Muzio, E. Dalla Valle, C. Nalini, A.
Torri, D. Sommariva and A. Branchi
Esterified Plant Stanol in Low-Fat Foods
P. Salo
Food Consumption in Poland in 1989-2000 and Cardiovascular Mortality
W. Sekuła,
W.B. Szostak and K. Figurska
Could a Nutraceutical Daily Assumption Significantly Improve the
Individual Cardiovascular Risk Profile?
A.F.G. Cicero, S. Linarello, A. Fiorito, S.
Nascetti, S. D’Addato and A. Gaddi
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